Trigonal tryptophane zipper as a novel building block for pH-responsive peptide nano-assemblies.
نویسندگان
چکیده
A novel C(3)-symmetric peptide conjugate bearing tryptophane zipper-forming peptides showed pH-responding self-assembly into nanospheres and nanofibers in water.
منابع مشابه
Syntheses and Self-assembling Behaviors of Pentagonal Conjugates of Tryptophane Zipper-Forming Peptide
Pentagonal conjugates of tryptophane zipper-forming peptide (CKTWTWTE) with a pentaazacyclopentadecane core (Pentagonal-Gly-Trpzip and Pentagonal-Ala-Trpzip) were synthesized and their self-assembling behaviors were investigated in water. Pentagonal-Gly-Trpzip self-assembled into nanofibers with the width of about 5 nm in neutral water (pH 7) via formation of tryptophane zipper, which irreversi...
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 1 شماره
صفحات -
تاریخ انتشار 2011